Basic Laboratory Methods in a Regulated Environment
Biotechnology transforms knowledge that emerges from life science research into technology, the creation of products of value to people. Beginning biotechnology students therefore need to develop a strong foundation in laboratory science that is integrated with an understanding of product quality. This course provides students with a foundation in basic concepts and techniques necessary to work as effective professionals in a biotechnology laboratory or small scale production facility. The course emphasizes metrology (the study of measurements), solution preparation, performing assays, and basic biological separation methods. These fundamental laboratory techniques are essential for student success in later molecular biology, cell culture, bioprocessing, analytical, and other specialized courses. Throughout the course the principles of product quality systems (e.g., Good Manufacturing/Laboratory Practices and ISO 9000) are integrated as students explore documentation, calibration, accuracy and precision, error reduction, trouble-shooting, verification and validation of assays, and other quality concepts. Integrating a "quality-mindset" into their laboratory work is important both for students who plan to work in a biotechnology company and for students who some day aspire to generate meaningful results in a research environment.
Submitted by Lisa Seidman ( LSeidman@MadisonCollege.edu) and Jeanette Mowery (JMowery@MadisonCollege.edu)
Published Textbooks:
- Required: Basic Lab Methods for Biotechnology 3rd edition by Lisa Seidman, Cynthia Moore, and Jeanette Mowery and Laboratory Manual for Biotechnology and Laboratory Science by Lisa Seidman, Mary Ellen Kraus, Diana Brandner and Jeanette Mowery.
- Recommended: Basic Laboratory Calculations for Biotechnology 2nd edition by Lisa Seidman
Additional materials*
- Syllabus
- Classroom Activities
- Lectures - video
- Lectures - Power point
- Instructors' notes for laboratory manual
- Sample final exam
*Course-in-a-Box access: To view additional materials, log in to your InnovATEBIO account. If you are a biotech faculty member at a college or high school, join InnovATEBIO to get an account. Note - it may take a few days to verify your faculty position and set up the account.
