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Biomanufacturing Monoclonal Antibodies Using NISTCHO Cells

Past Event
Antibodies bound to SARS-CoV-2 spike protein, image credit Sandra Porter
Event Date(s)
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In this workshop, participants will be introduced to experiments and techniques used in the upstream and downstream processes for monoclonal antibody production using NISTCHO cells. Two approaches will be taken; a low-tech approach for cell growth and mAb purification, and a high-tech approach using process-controlled bioreactors for cell growth and AKTA FPLC systems for protein purification. Biochemical QC techniques for determining purity, and titer will also be covered. Discussions and presentations will cover approaches to incorporating this material into courses and programs and examples ...
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ATE Project Talks: NISTCHO Cells for Teaching Biomanufacturing

Presentation
Description: NISTCHO cells are a newly released recombinant cell line that produce cNISTmAb, an industry relevant, open access monoclonal antibody to RSV. The NISTCHO cell line was developed by the National Institute of Standards and Technology (NIST) and MilliporeSigma and is available as a ...
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