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Antibodies bound to SARS-CoV-2 spike protein, image credit Sandra Porter
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In this workshop, participants will be introduced to experiments and techniques used in the upstream and downstream processes for monoclonal antibody production using NISTCHO cells. Two approaches will be taken; a low-tech approach for cell growth and mAb purification, and a high-tech approach using process-controlled bioreactors for cell growth and AKTA FPLC systems for protein purification. Biochemical QC techniques for determining purity, and titer will also be covered. Discussions and presentations will cover approaches to incorporating this material into courses and programs and examples ...
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The presentation described hackathons and how hackathons can be used for curriculum development and community building in biotech and emerging technologies. Two hackathon projects were discussed: Antibodies and AI, and NISTCHO. Several resources have been created through this project and are ...
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