SARS-CoV-2

This video shows how to:

1. Make a genome dataset and prepare a phylogenetic tree with viral genomes
2. Make a protein dataset and create a multiple alignment with sequences from spike proteins
3. Look at viral evolution in NextStrain.org
4. See where the D614G mutation ... View video

We discuss four kinds of projects that students can do to learn about molecular interactions between the novel SARS coronavirus and the cells it infects.

1. We use iCn3D to look at the SARS-CoV-2 spike protein in closed and open conformations.
2. We search for the human ACE2 gene ... View video