Developing CUREs for Antibody Engineering

Antibodies are arguably the most important class of proteins in biotechnology. These proteins are used in biological research, clinical diagnostic tests, therapeutic drugs, and laboratory services. Over 333 US employers in over 500 locations carry out research and / or manufacture products based on antibodies including rapid tests for COVID-19. The expanding use of antibodies as therapeutic drugs is spurring companies to hunt for antibodies with new specificities. At the same time, the challenges with antibody manufacturing and stability are encouraging companies to engineer these proteins to lower production costs. We are responding to the need for creating new antibodies and antibodies that can be manufactured more easily by developing research projects that incorporate related topics and technical skills. This talk will focus on the results of our first Antibody Engineering Hackathon, which we launched as a means to catalyze project creation and build a community of collaborators.

Speakers: Sandra Porter, PhD, Sheela Vemu, PhD

Team members:  Aron Kamajaya, PhD, Margaret Bryans, PhD, Sheela Vemu, PhD, Feather Ives, Todd Smith, PhD, Allissa Dillman, PhD,

• Learn more about the Antibody Engineers ATE project
• ATE-PI 2021 Antibody Engineers project video
• Read about the Antibody Engineering Hackathon 2022
• What did the student participants think? Read about one student's 2022 Antibody Hackathon Experience