Event Date(s): Monday, August 08, 2022 - 08:00am PDT to Thursday, August 11, 2022 - 05:00pm PDT
Register by: Monday, June 13 2022
Save the dates everyone!
The 2nd Virtual Hackathon for Developing CURES in Antibody Engineering will take place August 8-11th, 2022.
Application information will be available soon. Sign up for information and we will email you when it's time to apply.
This work is funded by a grant from the National Science Foundation's Advanced Technological Education program (DUE 2055036).
This event is free.
As a Hackathon participant, you will:
work in a team to research and develop antibody-related student research projects,
learn about antibodies and how they can be engineered
Learn about the use of antibodies in diagnostics, research, and therapeutics,
develop new skills in immunology-related bioinformatics programs and databases,
learn about new laboratory techniques for working with antibodies, and
become part of an exciting, fun, and collaborative community.
Faculty and students with varying levels of experience in working with antibodies are encouraged to apply. Participants will be selected based on experience and motivation to attend. Applicants from community colleges will receive the highest priority. Participants must be US-based.
Previous hackathon projects:
iCn3D for education: Participants will work to develop and test an essential feature set for an educational version of iCn3D.
Anti-SARS Antibodies vs Variants: This project focuses on identifying the interactions between commercial antibodies and the SARS-CoV-2 spike protein and making and testing predictions about the ability of commercial antibodies to neutralize the delta variant.
IEDB research projects: The IEDB (Immune Epitope Data Base) is an important tool for identifying and exploring the sequences and substances that are recognized by antibodies and T cell receptors. This project will address developing course-based research projects related to IEDB.
Break an Antibody: Antibody engineers need to understand the chemical interactions that hold antibodies and their target proteins together. In this project, students will use computational tools to identify interactions and make predications about amino acid changes that would cause the interactions to break. Students will mutagenize antibody clones to disrupt those interactions and compare the activity and specificity of the new versions with the original molecules.
Affordable Antibody Engineering: This project focuses on developing a low-tech antibody screening method (yeast display) for undergraduate classrooms. This method will enable academic institutions with low budgets to offer antibody engineering experience to their students without expensive equipment.